Toulouse University Hospital, Centre of PharmacoVigilance and Pharmacoepidemiology, Faculty of Medicine, Department of Medical and Clinical Pharmacology, 31000 Toulouse, France. Toulouse University Hospital, Centre of PharmacoVigilance and Pharmacoepidemiology, Faculty of Medicine, Department of Medical and Clinical Pharmacology, 31000 Toulouse, France. Electronic address: francois.montastruc@univ-tlse3.fr.